Make Your Prediction
Indianapolis Colts @ Buffalo Bills
41
VS
11/21/2021
Final
Final
15
Indianapolis vs Buffalo Top User Picks
Indianapolis Colts vs Buffalo Bills Preview November 21, 2021
Indianapolis Colts (5-5) is visiting Buffalo Bills (6-3) on November 21, 2021, 1:00 PM ET and playing at the Highmark Stadium.
The Buffalo Bills are favored by vegas at a line of -7. The opening line was -7.5 so the public has been betting on Indianapolis Colts causing the BUF line to shift +0.5. Get the consensus from the top 10 users most likely to be right on tonight's matchup below.
Indianapolis Highlights
Total Score
8th
15.76
Passing Yards
22nd
227.10
Rushing Yards
6th
136.30
Time on Field
10th
31:25
Number of Plays
18th
62.60
Yards per Play
12th
5.81
ATS Trends
- Indianapolis are 5-2 ATS in their last 7 games.
- The total has gone OVER in 5 of Indianapolis' last 7 games.
- Indianapolis are 4-1 SU in their last 5 games.
- Indianapolis are 8-4 SU in their last 12 games against Buffalo.
- The total has gone OVER in 6 of Indianapolis' last 7 games on the road.
- Indianapolis are 1-4 SU in their last 5 games when playing on the road against Buffalo.
- Indianapolis are 5-2 SU in their last 7 games this season.
- Indianapolis are 4-2 ATS in their last 6 games against an opponent in the American Football Conference conference.
- Indianapolis are 4-1 ATS in their last 5 games against an opponent in the American Football Conference East division.
Player Injuries
- Xavier Rhodes is OUT Sunday vs Jacksonville (Calf)
- Sam Tevi IR (ACL)
- Tyquan Lewis IR, is out for season (Knee)
- Nick Nelson IR (Undisclosed)
- Skai Moore IR (Back)
- Parris Campbell IR (Foot)
- Khari Willis IR (Calf)
- Julian Blackmon IR, is out for season (Achilles)
- Robert Windsor IR (Undisclosed)
- Quartney Davis IR (Shoulder)
Buffalo Highlights
Total Score
3rd
16.47
Passing Yards
6th
279.22
Rushing Yards
10th
121.89
Time on Field
7th
31:39
Number of Plays
6th
67.00
Yards per Play
6th
5.99
ATS Trends
- Buffalo are 14-5-1 ATS in their last 20 games.
- Buffalo are 14-4 SU in their last 18 games.
- The total has gone UNDER in 4 of Buffalo's last 5 games against Indianapolis.
- Buffalo are 10-1 SU in their last 11 games at home.
- Buffalo are 4-1 SU in their last 5 games when playing at home against Indianapolis.
- Buffalo are 1-5 ATS in their last 6 games against an opponent in the American Football Conference South division.
- Buffalo are 4-1 ATS in their last 5 games played in November.
- The total has gone UNDER in 6 of Buffalo's last 9 games when playing as the favourite.
- The total has gone UNDER in 5 of Buffalo's last 7 games played on a Sunday when at home.
Player Injuries
- Jon Feliciano IR (Calf)
- Mitchell Trubisky is "?" Sunday vs Indianapolis (COVID-19)
- Bryan Cox Jr. IR (Achilles)
- Tremaine Edmunds is "?" Sunday vs Indianapolis (Hamstring)
- Dawson Knox is out indefinitely (Hand)
- Marquez Stevenson IR (Foot)
